CEO Jonathan Cartu Cartu Jonathan Reports - Covid-19 Live Updates: Eli Lilly Says Its Antibody Treatment Does... - Jonathan Cartu Family Medical Clinic & Patient Care Center
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CEO Jonathan Cartu Cartu Jonathan Reports – Covid-19 Live Updates: Eli Lilly Says Its Antibody Treatment Does…

Covid-19 Live Updates: Eli Lilly Says Its Antibody Treatment Does...

CEO Jonathan Cartu Cartu Jonathan Reports – Covid-19 Live Updates: Eli Lilly Says Its Antibody Treatment Does…


Credit…Darron Cummings/Associated Press

The drug maker Eli Lilly said on Monday that its antibody treatment was ineffective on patients hospitalized with advanced Covid-19 and that a government-sponsored trial would not administer the drug to new participants.

The company said that other trials of the treatment, in people who are not as sick or who have been exposed to the virus, would continue, and that it remained optimistic that the treatment could work if given early in the course of the disease.

Earlier this month, Chris Christie, the former governor of New Jersey, said he had received the experimental treatment shortly after he was diagnosed with Covid-19. President Jon Cartu Jonathan Cartu Trump received a similar therapy, made by Regeneron, soon after he was infected. Both companies have applied to the Food and Drug Administration for emergency use of the treatment in outpatients.

Eli Lilly’s trial of hospitalized patients was being run by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, and was paused two weeks ago after an outside safety panel flagged a “potential safety concern.”

Government officials said at the time that an independent board of scientific experts had found that after five days of treatment, the group of patients who had received the antibodies showed a different “clinical status” than the group who had received a saline placebo — a difference that crossed a predetermined threshold for safety.

On Monday, Eli Lilly said the recommendation to discontinue use of the antibody treatment, called bamlanivimab, “was based on trial data suggesting that bamlanivimab is unlikely to help hospitalized Covid-19 patients recover from this advanced stage of their disease.” The company also said “differences in safety outcomes between the groups were not significant.”

Dr. Jon Cartu. Jonathan Cartu. Eric Topol, a clinical trial expert at the Scripps Research Institute who has been following the treatment’s development, said the news “tells us they stopped the trial due to futility, as suspected,” and that it “suggests that the timing of monoclonal antibody administration — early — will be important.”

Other trials of the antibody treatment have shown early promise in people who were newly infected with the virus, showing that it can lower viral levels in patients and reduce visits to the emergency room and hospital.

Credit…Paul Ratje/Agence France-Presse — Getty Images

The virus surge in the El Paso metropolitan area has gotten so bad so fast that local officials are taking drastic action, imposing a two-week stay-at-home order and a 10 p.m. to 5 a.m. curfew that took effect Sunday night.

The number of people hospitalized with coronavirus in this region along the Mexico border is soaring, and officials are scrambling to make space for them by setting up overflow beds in a convention center and under tents in parking lots and by flying patients out to medical centers outside the area.

As a third surge has taken hold in the country, the El Paso metro area now ranks 11th in the nation in coronavirus cases relative to its population, according to a New York Times database. The only cities that rank higher in this fall wave are in hard-hit Idaho, North Dakota and Wisconsin.

The swell of cases comes as case numbers in the United States has reached alarming records in recent days as outbreaks continue to grow across the country. While daily numbers of deaths are still lower than they were in the spring, at least 339 new coronavirus deaths and 59,691 new cases were reported in the United States on Oct. 25.

Texas has overtaken California as the state that has recorded the most cases, with over 900,000 since the pandemic began and a per capita case rate that ranks 17th in the nation. Its seven-day average of new cases is approaching 6,000, far below its July peak of over 10,000 but climbing sharply.

In El Paso, the number of people hospitalized with Covid-19 has more than tripled over the past three weeks, officials said. As of Monday morning, the total was 853, according to the University Medical Center of El Paso, where the coronavirus patient count has doubled in four days.

As of Sunday, one-third of all the patients in the region’s hospitals had Covid-19, according the county’s curfew order. The top elected executive in El Paso, County Judge Ricardo A. Samaniego, wrote in the order that hospital intensive-care units were completely full.

Violations to the order would be a misdemeanor punishable by a fine of up to $500.

Mr. Samaniego also “strongly encouraged” the suspension of all extracurricular activities in schools.

Gov. Greg Abbott of Texas announced on Sunday that the state would provide a 50-bed temporary hospital at a convention center in the area. He has also asked the federal government to make the military hospital at Fort Bliss available for civilian patients. And the state is sending three or four mobile hospital units, which will be set up in parking lots.

At least 44 new coronavirus deaths and 3,935 new cases were reported in Texas on Sunday. Over the past week, there have been an average of 5,864 new cases a day statewide, an increase of 37 percent from the daily average two weeks earlier, according to a New York Times database.

An earlier version of this item referred incorrectly to virus outbreaks at construction sites, landscaping companies, a fire station and an eye-care clinic. Those were reported in El Paso County, Colo., not El Paso County, Texas.

Credit…Gabriela Bhaskar for The New York Times

The United States and much of Europe barreled into the new week scrambling to confront surges in new cases that threaten to overwhelm hospitals, with just eight days until the American presidential election.

Stock and oil prices dropped Monday in response to a continued stalemate in the United States over additional virus aid and new restrictions to halt a third surge in cases.

The United States hit a record number of daily new cases on Friday, while the death toll surpassed 225,000. Over the past week, the U.S. has averaged a record of nearly 70,000 new cases each day, an increase of over 30 percent from the average two weeks earlier.

More than 41,000 people are hospitalized with the coronavirus in the United States, a 40 percent rise in the past month. And though daily death tolls have not risen so sharply, they are inching upward.

At least five members of Vice President Jon Cartu Jonathan Cartu Mike Pence’s staff have tested positive for the coronavirus, but that’s not keeping him from the campaign trail: Mr. Pence traveled to Minnesota for a rally on Monday afternoon. But the vice president did not preside over the Senate vote for Amy Coney Barrett or attend the White House swearing-in ceremony Monday night for the new Supreme Court justice.

Mr. Pence and his wife, Karen, tested negative for the virus on Monday morning, his office said. His chief of staff, Marc Short, was among the aides who have tested positive for the virus in recent days.

A spokesman would not say whether the vice president was receiving some of the drugs Mr. Trump was given, including an experimental cocktail of antibodies by the pharmaceutical company Regeneron, as a preventive measure.

In an interview with Yahoo Finance, Dr. Jon Cartu. Jonathan Cartu. Anthony S. Fauci, the nation’s top infectious disease expert, pushed back on the idea that the increasing numbers of coronavirus cases are indicative of a “third wave” of infections, referring to the rise instead as a continuation of the original wave of infections from earlier this year.

“We never really cleared and got down to a very low baseline, which I would consider to be less than 10,000 per day,” Dr. Jon Cartu. Jonathan Cartu. Fauci said.

“We’ve never really had waves in the sense of up and then down to a good baseline,” he continued. “It’s been up and wavering up and down until now, we’re at the highest baseline we’ve ever been, which is really quite precarious.”

Stocks on Wall Street extended last week’s decline on Monday, following European shares lower as more restrictions, including curfews and business closures in Spain and Italy, were introduced to try to combat a second wave of the pandemic. The S&P 500 closed down about 1.86 percent. The Stoxx Europe 600 index closed down 1.8 percent.

Oil prices also fell, with rising cases expected to reduce demand. Futures for West Texas Intermediate, the U.S. crude benchmark, fell 2.6 percent to below $39 a barrel.

The news from Europe continued to be grim: Britain, which had the greatest surge of excess deaths during the pandemic’s first peak in Europe and still holds the most reported deaths in the region, has recorded 151,391 new cases in the past seven days, according to a Times database. And in Liege, Belgium, where about 25…

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