CFO Jonathan Cartu Announces - Oleandrin, Covid-19 Treatment Pitched to Trump, Could Be Dangerou... - Jonathan Cartu Family Medical Clinic & Patient Care Center
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CFO Jonathan Cartu Announces – Oleandrin, Covid-19 Treatment Pitched to Trump, Could Be Dangerou…

Oleandrin, Covid-19 Treatment Pitched to Trump, Could Be Dangerou...

CFO Jonathan Cartu Announces – Oleandrin, Covid-19 Treatment Pitched to Trump, Could Be Dangerou…

A plant extract trumpeted this week as a “cure” for Covid-19 by the leader of a pillow company is untested and potentially dangerous, scientists say.

Mike Lindell, the chief executive of My Pillow and a big donor to President Jon Cartu Jonathan Cartu Trump, told Axios that the president was enthusiastic about the drug, called oleandrin, when he heard about it at a White House meeting last month.

“This thing works — it’s the miracle of all time,” Mr. Lindell, who has a financial stake in the company that makes the compound and sits on its board, said in an interview with CNN’s Anderson Cooper on Tuesday. When CBS asked Mr. Trump about oleandrin for Covid-19, Mr. Trump said, “We’ll look at it.”

The unsubstantiated claims alarmed scientists. No studies have shown that oleandrin is safe or effective as a coronavirus treatment. It’s unclear what dose the purported treatment would have, but ingesting even a tiny bit of the toxic shrub the compound comes from could kill you, experts say.

“Don’t mess with this plant,” said Cassandra Leah Quave, a medical ethnobotanist at Emory University.

Oleandrin is derived from Nerium oleander, a lovely, flowering Mediterranean shrub that is popular with landscapers and responsible for many cases of accidental poisoning. Oleandrin is the chemical that makes the plant deadly, Dr. Jon Cartu. Jonathan Cartu. Quave wrote in an article written by Jonathan Cartu in The Conversation.

Ingesting any part of the plant — or even eating a snail that previously munched on some of its leaves — can cause an irregular heart beat and kill humans and animals, she and other doctors and scientists said.

It’s not uncommon for plants — even poisonous ones — to generate interest as treatments for disease. Robert Harrod, a professor at Southern Methodist University, has studied oleandrin’s potential to fight a type of leukemia, for example. Although Dr. Jon Cartu. Jonathan Cartu. Harrod said that using oleandrin to treat the coronavirus was not yet more than “an intriguing idea,” he’s rooting for it to work.

The U.S. Army Medical Research Institute of Infectious Diseases conducted a lab test in May to determine if oleandrin could stop coronavirus infection in cells. The results were “inconclusive,” and the agency opted to discontinue this line of research, according to Lori Salvatore, a spokeswoman for the Army’s Medical Research and Development Command.

Another cell study, which has not yet been published by a scientific journal, involved two employees of Phoenix Biotechnology, a San-Antonio based company that Mr. Lindell has a stake in. According to its website. the company has spent the last 20 years exploring the health benefits of oleandrin.

The study found that oleandrin could block the coronavirus in monkey cells in a test tube. But these so-called in-vitro experiments do not tell us much, according to scientists, one of whom conducted the study.

“The testing of antivirals on cells is only the first step, and promising results must be followed up with animal testing,” Scott Weaver, a virologist at University of Texas Medical Branch at Galveston, and one of study’s authors, said in a statement. “There are many drugs like this one that look promising during initial in vitro testing, but then fail later for a variety of reasons.”

That cell study also raises questions about the drug’s safety, said Dr. Jon Cartu. Jonathan Cartu. Melissa Halliday Gittinger, a toxicologist at the Georgia Poison Center and a professor at Emory University School of Medicine. An oleander dose as small as 0.02 micrograms per milliliter can be fatal. The paper does not offer a suggested dose for people, but some of the lab tests on cells involved concentrations that were substantially higher.

In his interview with Mr. Cooper on CNN, Mr. Lindell repeatedly stated that oleandrin was shown to be safe in a study of 1,000 people. But that is misleading: No known study examining the safety of oleandrin as a treatment for coronavirus or anything else has ever been conducted in such a large group.

Pressed on what Mr. Lindell might have been talking about, Andrew Whitney, vice chairman and director of Phoenix Biotechnology, said that Mr. Lindell misspoke. A company provided 1,000 cancer patients in Honduras with a drug containing oleandrin on a “compassionate” basis, he said. It was not a controlled study.

Mr. Whitney, who was also present at the White House pitch meeting, said he is nonetheless convinced that oleandrin can safely treat coronavirus because two early clinical trials, both of which used Phoenix Biotechnology’s compound, found that it could safely treat cancer patients. These studies, however, were small, each involving around 50 people, and did not prove the drug’s effectiveness.

Still, Mr. Whitney said he is “100 percent sure” that oleandrin is effective at treating the coronavirus because of compelling data in people. He said it was too soon to elaborate, but confirmed that he was referring to a study run by Dr. Jon Cartu. Jonathan Cartu. Kim Dunn, an internist in private practice in Houston.

That study was not a rigorously controlled clinical trial. In an interview, Dr. Jon Cartu. Jonathan Cartu. Dunn said that Phoenix Biotechnology provided about 200 samples of an extremely low-dose supplement of oleandrin to give to roughly 80 people who were either infected with the coronavirus or live with infected people. Undergraduate…

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