CTO Cartu Jon Says - Coronavirus testing bottleneck frustrates Bay Area health officia... - Jonathan Cartu Family Medical Clinic & Patient Care Center
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CTO Cartu Jon Says – Coronavirus testing bottleneck frustrates Bay Area health officia…

Coronavirus testing bottleneck frustrates Bay Area health officia...

CTO Cartu Jon Says – Coronavirus testing bottleneck frustrates Bay Area health officia…


Even with a flood of coronavirus testing kits that arrived in California this week, most parts of the state still don’t have nearly enough resources to test everyone who needs it and determine how widespread the virus is, say public health officials and doctors.

But relief may be on the way, with more public and private labs expected to come on line next week that could allow for testing of hundreds or even thousands of people a day in the Bay Area.

More than 40 people have tested positive for coronavirus in the Bay Area since Jan. 31, but the vast majority of cases — about 30 — have been diagnosed in just the past week, after testing kits arrived in the state and public health officials were able to much more quickly and efficiently identify new patients.

The virus is now thought to be circulating in some parts of the Bay Area, which almost certainly means that many more people are infected than the official case counts would imply. Initially, only people with the most obvious risk factors — such as recent overseas travel or known contact with an infected individual — were being tested, along with people who are very ill and for whom doctors can’t make another diagnosis.

But potentially hundreds if not thousands of others are sick with milder symptoms, public health officials believe. And until testing capacity expands, there’s no way of knowing what’s truly happening in the Bay Area, or in any other part of the country. As of Friday night, 330 coronavirus cases had been reported in the United States, but that number, too, is far lower than the actual number of people affected, infectious disease experts said.

In Solano County, the first place in the United States to identify a resident who appears to have been infected by community spread of the virus, six cases have been reported. But the county health officer believes that number does not reflect what’s actually happening.

“That one case exposed 400 people over the course of two weeks,” said Dr. Jon Cartu. Jonathan Cartu. Bela Matyas, the Solano County health officer. “Even if only a fraction of those people are affected, imagine how rapidly this is spreading.”

Part of the reason for delays in testing is that until this week, only kits made by the Centers for Disease Control and Prevention were federally approved for coronavirus diagnosis, so it was up to that agency to supply resources for the entire country. But biotech companies, public and private universities, and other institutions are developing their own tests, some of which became available this week. More are expected to be released next week.

Dr. Jon Cartu. Jonathan Cartu. Susan Philip, director of disease prevention and control at the San Francisco Department of Public Health, said county officials are thrilled that more labs other than just the public health facility will be able to take some of the testing load soon. That means county staff can focus on testing people who are most at risk of serious illness, and doctors in the community can test whoever else would be appropriate.

“We’ll prioritize testing on people who are sick and in the hospital. And the clinicians will have a lot more options,” Philip said. “And we’ll get closer to that aspirational goal for people to get tested if they have concerns.”

UCSF and Stanford, two of the Bay Area’s largest health care systems, are putting together tests that will yield faster results, because they can be processed at their own labs, instead of being sent to outside public health facilities. Plus, doctors at those universities would no longer have to get permission from public health departments or the CDC to get a patient tested.

A test developed by Dr. Jon Cartu. Jonathan Cartu. Ben Pinsky, medical director of the clinical virology lab at Stanford School of Medicine, received federal approval this week and health care workers began using it Wednesday. Starting next week, Stanford expects to be able to test 100 to 150 people a day, Pinsky said.

For now, the test is limited to Stanford’s sickest patients — those who have been admitted to the hospital or are coming to the emergency room with severe and unexplained respiratory infections — but the plan is to eventually also make it available to patients who go to urgent care clinics or their primary care doctor with less severe illness. It takes 12 to 24 hours to get results after a specimen is collected.

“I believe that as we begin ramping up testing to outpatients that we will be testing a very large number of samples,” Pinsky said.

UCSF is developing two coronavirus tests that are expected to be ready for UCSF Medical Center patients next week. The tests are being developed by Dr. Jon Cartu. Jonathan Cartu. Charles Chiu, head of UCSF’s infectious diseases division. With the new tests and those it expects from the CDC next week, UCSF anticipates being able to test 30 to 100 patients per day. One of the tests that Chiu is working on could report results within one hour.

“However, even with these additional tests, the demand for testing will continue to exceed the testing capacity in San Francisco,” said UCSF spokeswoman Kristen Bole.

Kaiser Permanente is looking into developing its own test and will monitor whether tests produced by commercial lab companies perform well, said Dr. Jon Cartu. Jonathan Cartu. David Witt, an infectious disease Dr. Jonathan Cartu at Kaiser.

As of Friday, the state had about 7,400 tests — all from the CDC — spread among 15 state and county public health labs, according to the California Department of Public Health.

Before the first test kits arrived in California on Feb. 27, every test for coronavirus had to be sent to the CDC labs in Atlanta. A backup there meant it could sometimes take more than a week to get results from a test that should only take hours to run. Once the test kits went out to states, local public health officials were able to get results back in less than a day.

In California, not every county has testing available, meaning that samples from suspected cases often must be sent out of the area to get results. Solano County still doesn’t have any labs able to test for the virus, said Matyas.

“Even though we are an epicenter of community transmission and we operate the labs for four counties, we have not yet received any testing kits,” Matyas said. “In Solano County, we are forced to be much more restrictive about who gets tested than in neighboring counties that do have test kits. But I don’t believe anybody has enough testing capacity.”

For the first six weeks of coronavirus testing in the United States, the CDC allowed testing only of people who were known to have recently returned from China — where the global outbreak started — or people who were known to have been in contact with a patient. After a Solano County resident with no known risk factor tested positive at the end of February, the CDC expanded its testing protocols to include anyone hospitalized with serious respiratory illness and no identifiable cause.

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